Recipient of the 2007 Golden Globe Award for Best Drama Television Series and multiple Emmy nominations, including Outstanding Drama Series for the past two years, "Grey's Anatomy" returns to the ABC Television Network for its fifth season.
　　Is "happily ever after" possible for Meredith Grey and Derek "McDreamy" Shepherd? With Meredith experiencing a breakthrough in therapy - the realization that she and Derek can be extraordinary together, rather than ordinary ap -- she and Derek now face the highs and lows of being a mitted uple.
　　Continuing their first year as residents at Seattle Grace Hospital, Meredith, Cristina Yang, Izzie Stevens and Alex Karev have interns of their own to mentor, including Meredith's half-sister, Lexie Grey. Lexie has bee a roommate and nfidante to Gee O'Malley, who, after divorce with Callie, a breakup with Izzie, and learning that he failed his residency test by only one point, is striving to get both his fessional and personal life back on track.
　　After attending to his girlfriend Rebea's mental illness on his own, and revealing that he had gone through this with his own mother, Alex finds solace in Izzie's arms. Alex must ntinue through this difflt time, whether or not Izzie remains by his side.
　　Cristina, having finally won out over her tough-as-nails mentor, Erica, is back on track as a surgeon - but is there a chance for new love in her life as well?
　　With the enuragement of Mark "McSteamy" Sloan, Dr. Callie Torres has taken a chance on love with cardiothoracic surgeon, Erica Hahn; now, she and Erica must figure out what happens after the first kiss.
　　Overseeing the residents is the no-nonsense Chief Resident, Miranda Bailey. Facing marital troubles and the difflty of balancing her work and personal life, Bailey has handed her responsibilities as head of the free clinic over to Izzie. Also striving for balance is Chief of Surgery, Richard Webber, who has reunited with his estranged wife, Adele.
　　The doctors of Seattle Grace Hospital deal with life-or-death nsequences on a daily basis - it's in one another that they find fort, friendship and love. Together they're disvering that neither medicine nor relationships can be defined in black and white. Real life only es in shades of grey.
　　"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Katherine Heigl as Isobel "Izzie" Stevens, Justin Chambers as Alex Karev, T.R. Knight as Gee O'Malley, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Chyler Leigh as Lexie Grey, and Brooke Smith as Erica Hahn.